Matched unrelated bone marrow transplantation for combined immunodeficiency
نویسندگان
چکیده
منابع مشابه
Neonatal bone marrow transplantation for severe combined immunodeficiency.
AIMS To evaluate outcome following neonatal bone marrow transplantation (BMT) for severe combined immunodeficiency (SCID) when there is a family history of a previously affected sibling, and to compare results with those published for in utero BMT. METHODS A retrospective review of cases referred and transplanted between 1987 and 1999, focusing on infectious and graft versus host disease (GvH...
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Although some trials have allowed matched or single human leukocyte antigen (HLA)-mismatched related donors (mmRDs) along with HLA-matched sibling donors (MSDs) for pediatric bone marrow transplantation in early-stage hematologic malignancies, whether mmRD grafts lead to similar outcomes is not known. We compared patients < 18 years old reported to the Center for International Blood and Marrow ...
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متن کاملLess Graft-Versus-Host Disease after Rabbit Antithymocyte Globulin Conditioning in Unrelated Bone Marrow Transplantation for Leukemia and Myelodysplasia: Comparison with Matched Related Bone Marrow Transplantation
One of the major drawbacks for unrelated donor (UD) bone marrow transplantation (BMT) is graft-versus-host disease (GVHD). Despite results from randomized trials, antithymocyte globulin (ATG) is not routinely included for GVHD prophylaxis in UD BMT by many centers. One of ways to demonstrate the usefulness of rabbit ATG in UD BMT is to evaluate how its results approximate to those observed in m...
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ژورنال
عنوان ژورنال: Bone Marrow Transplantation
سال: 2000
ISSN: 0268-3369,1476-5365
DOI: 10.1038/sj.bmt.1702215